(R)-3-Amino-3-(3-Nitro-Phenyl)-Propionic Acid - Names and Identifiers
(R)-3-Amino-3-(3-Nitro-Phenyl)-Propionic Acid - Physico-chemical Properties
Molecular Formula | C9H10N2O4
|
Molar Mass | 210.19 |
Density | 1.404g/cm3 |
Boling Point | 384.5°C at 760 mmHg |
Flash Point | 186.4°C |
Vapor Presure | 1.34E-06mmHg at 25°C |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
Refractive Index | 1.612 |
(R)-3-Amino-3-(3-Nitro-Phenyl)-Propionic Acid - Introduction
(R)-3-Amino-3-(3-nitrophenyl)propionic acid, also known as (R)-3-AAPP, is an organic compound. The following is an introduction to its nature, use, preparation and safety information:
Nature:
1. Appearance: colorless crystal
2. molecular formula: C9H10N2O4
3. Molecular weight: 214.19g/mol
4. Melting point: 106-108°C
5. Solubility: low solubility in water, soluble in organic solvents such as methanol, dimethylformamide, etc.
Use:
(R)-3-Amino-3-(3-nitrophenyl)propionic acid is commonly used as a chiral ligand and intermediate. It has important application value in the synthesis of drugs, and can be used in the synthesis of chemicals, pesticides, anti-tumor drugs. In addition, it can also be used for catalysts and catalyst supports in organic synthesis reactions.
Preparation Method:
The preparation of (R)-3-Amino-3-(3-nitrophenyl)propionic acid is complicated, generally starting from the commercially available starting material (Br)-(3-nitrophenyl)-propionic acid. Specific steps include hydrazination, substitution, amination and racemization reactions. The preparation process requires certain organic synthesis techniques and equipment.
Safety Information:
1. (R)-3-Amino-3-(3-nitrophenyl)propionic acid is an organic compound, which is dangerous and needs to be operated in a suitable laboratory environment.
2. contact with eyes, skin or inhalation of its dust may cause irritation or allergic reaction, need to comply with the safety practice, the use of personal protective equipment.
3. avoid contact with oxidant, magnesium powder and other flammable substances to prevent safety accidents.
4. During use and storage, it is strictly forbidden to contact it with food or drinking water.
5. When handling (R)-3-Amino-3-(3-nitrophenyl)propionic acid, follow local environmental regulations and chemical safety measures. When waste is discarded, it should be disposed of in accordance with relevant regulations.
Last Update:2024-04-09 20:52:54